Tag
Xenobiotics
9 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1048943 | CYP1A1 Ile462Val (*2C) | Phase I detoxification enzyme that activates polycyclic aromatic hydrocarbons... | Methylation & Detox | Strong | |
| rs2032582 | ABCB1 G2677T/A (Ser893Ala/Thr) | Triallelic missense variant in the P-glycoprotein efflux pump that reduces th... | Gamete Quality & DNA Repair | Moderate | |
| rs4646903 | CYP1A1 *2A (MspI, T3801C) | Regulatory variant in the 3'-flanking region of CYP1A1 that increases gene in... | Dental & Oral Health | Moderate | |
| rs1208 | NAT2 R268K | NAT2 acetylation speed tag SNP - marks rapid vs slow acetylator haplotypes | Methylation & Detox | Established | |
| rs1799930 | NAT2 R197Q | Slow acetylator variant affecting Phase II detoxification capacity | Methylation & Detox | Established | |
| rs1801280 | NAT2 I114T | Phase II detoxification - acetylation of aromatic amines and certain medications | Methylation & Detox | Established | |
| rs366631 | GSTM1 Tag SNP for gene deletion | Tag SNP proxy for GSTM1 gene deletion status — the most common pharmacogenomi... | Methylation & Detox | Strong | |
| rs2602899 | ADH5 ADH5 Promoter NF-kB Variant | Regulatory SNP in the ADH5 promoter at a potential NF-kB binding site; the pr... | Allergy & Atopic Disease | Moderate | |
| rs71748309 | GSTT1 Null (Gene Deletion) | Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac... | Methylation & Detox | Strong |