Research
Tag

Stress Response

24 genetic variants with this tag.

RSID Gene Description Category
rs1049353 CNR1 3'UTR (G1359A) Synonymous exon 4 variant in the cannabinoid receptor 1 gene; near an exon sp... Mood & Behavior Moderate
rs10482605 NR3C1 NR3C1 promoter variant reducing glucocorticoid receptor transcription; G alle... Longevity & Aging Moderate
rs10515522 NR3C1 Intronic NR3C1 variant associated with longevity in Polish nonagenarians and ... Longevity & Aging Emerging
rs12402521 PDC Intronic PDC variant in the phosducin gene — G homozygotes show 12–15 mmHg hi... Coronary Artery Disease & Atherosclerosis Moderate
rs12624433 SLC12A5 KCC2 Chloride Transport Intronic variant in SLC12A5 reducing KCC2 potassium-chloride cotransporter fu... Mood & Behavior Moderate
rs1743963 SGK1 Intronic SGK1 variant associated with depression susceptibility in coronary h... Blood Pressure & Hypertension Emerging
rs11545787 RASD1 RASD1 photic entrainment variant 3' UTR variant in RASD1 (Dexras1), a GTPase that gates light signals to the c... Hormones & Sleep Strong
rs1545843 SLC6A15 SLC6A15 depression risk variant Intronic variant reducing SLC6A15 expression in hippocampus; AA carriers show... Mood & Behavior Strong
rs137852689 STAR R217T (Arg217Thr) Pathogenic STAR variant that abolishes steroidogenic acute regulatory protein... Reproductive Hormones Established
rs16147 NPY C-399T Promoter variant in neuropeptide Y that modulates NPY expression under stress... Mood & Behavior Moderate
rs258750 NR3C1 NR3C1 Intronic Variant (c.2181+244A>G) Intronic NR3C1 variant tagging glucocorticoid receptor gene haplotype blocks ... Reproductive Hormones Moderate
rs2023239 CNR1 Intronic variant near the CNR1 exon 3 alternative promoter that modulates CB1... Mood & Behavior Moderate
rs2883929 NR3C2 NR3C2 I3 intron variant Intronic variant in the mineralocorticoid receptor gene associated with alter... Reproductive Hormones Moderate
rs11683424 DNMT3A Intronic variant in the de novo DNA methyltransferase DNMT3A, associated with... Methylation & Detox Emerging
rs324420 FAAH Pro129Thr Affects anandamide levels through altered FAAH enzyme stability, influencing ... Mood & Behavior Strong
rs35936514 LHPP LHPP depression risk variant Intronic/3'UTR variant in LHPP, a histidine phosphatase essential for stress ... Mood & Behavior Strong
rs41423247 NR3C1 BclI Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s... Mood & Behavior Strong
rs4570625 TPH2 G-703T Promoter variant affecting brain serotonin synthesis enzyme; influences emoti... Mood & Behavior Moderate
rs6757908 EIF2AK3-AS1 Rare intronic variant in EIF2AK3-AS1, an antisense long non-coding RNA that r... Endometriosis & Uterine Health Emerging
rs72704544 GPM6A GPM6A Neuronal Membrane Glycoprotein Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do... Mood & Behavior Moderate
rs9556979 STK24 HPA Axis Regulation Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur... Mood & Behavior Moderate
rs6198 NR3C1 3'UTR variant that increases glucocorticoid-resistant GRβ isoform expression,... Longevity & Aging Strong
rs9470080 FKBP5 Intronic FKBP5 variant in the stress-aging haplotype block — T allele carrier... Longevity & Aging Strong
rs9402571 SGK1 Regulatory variant in SGK1 (serum/glucocorticoid regulated kinase 1) — the mi... Blood Sugar & Diabetes Moderate