Tag
Serotonin
15 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs104893665 | SPR Arg150Gly | Pathogenic missense variant in sepiapterin reductase that abolishes BH4 biosy... | Vitamins & Nutrient Absorption | Established | |
| rs10514299 | TMEM161B-MEF2C TMEM161B-MEF2C intergenic variant | Intronic variant near the MEF2C transcription factor locus associated with in... | Mood & Behavior | Strong | |
| rs121917746 | SPR Q119X | Nonsense variant in sepiapterin reductase that abolishes BH4 biosynthesis, ca... | Vitamins & Nutrient Absorption | Established | |
| rs121917747 | SPR | Nonsense variant in sepiapterin reductase creating a premature stop codon (p.... | Vitamins & Nutrient Absorption | Established | |
| rs1800883 | HTR5A | Promoter/5' UTR variant in the serotonin 5-HT5A receptor gene affecting recep... | Mood & Behavior | Moderate | |
| rs17679445 | PNPO Arg116Gln | Missense variant in pyridoxamine 5'-phosphate oxidase that reduces the enzyme... | Hormones & Sleep | Moderate | |
| rs2050122 | HTR6 | Regulatory variant near the HTR6 serotonin 6 receptor gene associated with ch... | Hormones & Sleep | Moderate | |
| rs4570625 | TPH2 G-703T | Promoter variant affecting brain serotonin synthesis enzyme; influences emoti... | Mood & Behavior | Moderate | |
| rs4702 | FURIN proBDNF Processing Variant | A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si... | Mood & Behavior | Moderate | |
| rs6295 | HTR1A C-1019G | Functional promoter variant in the serotonin 1A receptor gene that increases ... | Mood & Behavior | Strong | |
| rs2325751 | PNPO | Regulatory variant 2 kb upstream of PNPO that may alter expression of the vit... | Hormones & Sleep | Emerging | |
| rs72704544 | GPM6A GPM6A Neuronal Membrane Glycoprotein | Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do... | Mood & Behavior | Moderate | |
| rs3816183 | HAAO Ile37Val | Missense variant in the kynurenine pathway enzyme HAAO that shifts tryptophan... | Hormones & Sleep | Moderate | |
| rs387907200 | SPR | Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe... | Methylation & Detox | Strong | |
| rs6795209 | HTR1F | Intergenic variant at the HTR1F locus on chromosome 3; the minor A allele inc... | Neurology & Cognition | Strong |