Tag
Satiety
16 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10767664 | BDNF | Obesity GWAS locus in a conserved BDNF enhancer - reduces hypothalamic BDNF e... | Appetite & Obesity | Strong | |
| rs1137101 | LEPR Q223R (Gln223Arg) | Common leptin receptor variant in the leptin-binding domain affecting satiety... | Hormones & Sleep | Moderate | |
| rs11152221 | MC4R MC4R Proximal LD Block Variant | Intergenic variant in the proximal 3' regulatory block near MC4R associated w... | Appetite & Obesity | Strong | |
| rs1943226 | MC4R MC4R third tagSNP | Upstream regulatory tag variant ~3 kb proximal to MC4R, included in MC4R hapl... | Appetite & Obesity | Emerging | |
| rs2922126 | GHSR GHSR A/G (rs2922126) | Upstream regulatory variant near the ghrelin receptor gene; the A allele is a... | Appetite & Obesity | Moderate | |
| rs476828 | MC4R MC4R-region BMI variant | Intergenic variant in the MC4R regulatory haplotype block, tagging the same a... | Appetite & Obesity | Strong | |
| rs489693 | MC4R MC4R AIWG variant | Intergenic variant near MC4R with genome-wide significant association with an... | Appetite & Obesity | Strong | |
| rs490683 | GHSR GHSR Promoter NF-1 Site Variant | Promoter variant in the ghrelin receptor gene that disrupts NF-1 transcriptio... | Appetite & Obesity | Moderate | |
| rs571312 | MC4R MC4R Regulatory Variant (Appetite Signaling) | Regulatory variant upstream of MC4R associated with increased caloric intake,... | Appetite & Obesity | Strong | |
| rs6232 | PCSK1 PCSK1 N221D (Asn221Asp) | Missense variant in PCSK1 encoding an Asn221Asp substitution near the Ca-1 ca... | Appetite & Obesity | Strong | |
| rs6234 | PCSK1 PCSK1 Q665E (Gln665Glu) | Missense variant in PCSK1 that causes a Gln665Glu substitution in the C-termi... | Appetite & Obesity | Strong | |
| rs696217 | GHRL Leu72Met | Missense variant in the ghrelin prepropeptide that impairs postprandial ghrel... | Appetite & Obesity | Moderate | |
| rs7799039 | LEP G-2548A | Promoter variant that increases leptin gene expression in adipose tissue, ele... | Appetite & Obesity | Moderate | |
| rs3211867 | CD36 | Intronic CD36 variant that reduces CD36 expression, impairing postprandial fa... | Triglycerides & Fatty Acids | Moderate | |
| rs9819506 | GHSR GHSR Promoter Variant (Ghrelin Receptor Signaling) | Promoter-region tag SNP in the ghrelin receptor gene associated with body wei... | Appetite & Obesity | Moderate | |
| rs5085 | APOA2 APOA2 rs5085 | Intronic APOA2 tag SNP that captures the saturated fat-weight gain interactio... | Triglycerides & Fatty Acids | Strong |