Tag
Phase II
11 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1138272 | GSTP1 Ala114Val | Second functional variant in glutathione S-transferase Pi 1, reducing enzyme ... | Methylation & Detox | Moderate | |
| rs1208 | NAT2 R268K | NAT2 acetylation speed tag SNP - marks rapid vs slow acetylator haplotypes | Methylation & Detox | Established | |
| rs1695 | GSTP1 Ile105Val | Phase II detoxification enzyme that conjugates glutathione to carcinogens, dr... | Methylation & Detox | Strong | |
| rs17309872 | GSS | Downstream regulatory variant of glutathione synthetase (GSS) associated with... | Methylation & Detox | Moderate | |
| rs1799930 | NAT2 R197Q | Slow acetylator variant affecting Phase II detoxification capacity | Methylation & Detox | Established | |
| rs1800566 | NQO1 Pro187Ser (C609T) | Phase II detoxification enzyme that reduces quinones and recycles CoQ10 to it... | Methylation & Detox | Strong | |
| rs1801280 | NAT2 I114T | Phase II detoxification - acetylation of aromatic amines and certain medications | Methylation & Detox | Established | |
| rs887829 | UGT1A1 UGT1A1*80 | Promoter variant in UGT1A1 that tags the *28 reduced-expression haplotype; T ... | Vascular Inflammation & Remodeling | Strong | |
| rs366631 | GSTM1 Tag SNP for gene deletion | Tag SNP proxy for GSTM1 gene deletion status — the most common pharmacogenomi... | Methylation & Detox | Strong | |
| rs4148323 | UGT1A1 *6 Gly71Arg | Phase II glucuronidation enzyme that metabolizes bilirubin and many drugs inc... | Pharmacogenomics | Established | |
| rs71748309 | GSTT1 Null (Gene Deletion) | Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac... | Methylation & Detox | Strong |