Tag
Phase I
8 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1048943 | CYP1A1 Ile462Val (*2C) | Phase I detoxification enzyme that activates polycyclic aromatic hydrocarbons... | Methylation & Detox | Strong | |
| rs4646903 | CYP1A1 *2A (MspI, T3801C) | Regulatory variant in the 3'-flanking region of CYP1A1 that increases gene in... | Dental & Oral Health | Moderate | |
| rs1056836 | CYP1B1 Leu432Val | Phase I detoxification enzyme that hydroxylates estradiol to potentially geno... | Methylation & Detox | Moderate | |
| rs1341162 | CYP2C8 | Intronic CYP2C8 haplotype-tagging variant linked to altered drug metabolism c... | Pharmacogenomics | Moderate | |
| rs4646438 | CYP3A4 *6 (17776insA / frameshift) | Frameshift insertion in CYP3A4 exon 9 that produces a truncated, non-function... | Pharmacogenomics | Strong | |
| rs4646976 | CYP2E1 | CYP2E1 intronic haplotype tag — affects enzyme activity and susceptibility to... | Pharmacogenomics | Moderate | |
| rs67784355 | CYP3A4 *11 (Thr363Met) | Rare missense variant in CYP3A4 that reduces protein expression and enzymatic... | Pharmacogenomics | Emerging | |
| rs72547516 | CYP1A2 Ile386Val | Rare CYP1A2 missense variant (Ile386Val) associated with potentially reduced ... | Pharmacogenomics | Emerging |