Tag
Periodontal Disease
8 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1047031 | DEFB1 | 3'UTR variant in the beta-defensin 1 gene that disrupts a microRNA binding si... | Dental & Oral Health | Moderate | |
| rs1143627 | IL1B -31T>C | Promoter variant that elevates IL-1β transcription, increasing risk of H. pyl... | TNF, NF-kB & Inflammatory Cytokines | Strong | |
| rs1143634 | IL1B +3954C>T | Synonymous exon 5 variant in IL-1β that increases IL-1β protein secretion des... | TNF, NF-kB & Inflammatory Cytokines | Strong | |
| rs17561 | IL1A Ala114Ser | Missense variant in IL-1α (Ala114Ser) that acts as a common hypomorphic mutat... | TNF, NF-kB & Inflammatory Cytokines | Moderate | |
| rs1360590 | CDKN2BAS | Intronic variant in ANRIL at the 9p21.3 locus — the shared susceptibility reg... | Coronary Artery Disease & Atherosclerosis | Moderate | |
| rs2234663 | IL1RN | Intron 2 VNTR polymorphism in IL1RN that alters IL-1Ra isoform balance and is... | TNF, NF-kB & Inflammatory Cytokines | Strong | |
| rs4252130 | PLG PLG promoter/intronic variant | Intronic PLG variant tagging a regional haplotype that reduces plasminogen ex... | Innate Immunity & Infection Defense | Moderate | |
| rs6596473 | SLC23A1 SLC23A1 variant | Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... | Vitamins & Nutrient Absorption | Emerging |