Tag
Parkinson's
21 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10839553 | CCKBR | Intronic variant near the cholecystokinin B receptor gene associated with res... | Neurology & Cognition | Strong | |
| rs117896735 | INPP5F | Intronic variant in the INPP5F/BAG3 locus associated with increased risk of R... | Neurology & Cognition | Strong | |
| rs11931074 | SNCA | SNCA 3′-region variant in the extended 3′ UTR that affects alpha-synuclein mR... | Neurology & Cognition | Strong | |
| rs199347 | GPNMB | Intronic GPNMB variant that acts as a brain eQTL; the A allele increases GPNM... | Longevity & Aging | Strong | |
| rs12752133 | GBA | Intronic GBA variant associated with REM sleep behavior disorder via lysosoma... | Neurology & Cognition | Strong | |
| rs17649553 | MAPT H1/H2 Haplotype Tag | Haplotype-tagging variant distinguishing MAPT H1 and H2 clades, affecting ris... | Neurology & Cognition | Strong | |
| rs17651213 | MAPT Exon 3 Splice Regulator | Intronic MAPT variant that directly regulates tau exon 3 splicing via differe... | Neurology & Cognition | Strong | |
| rs1800547 | MAPT H1/H2 Haplotype Splice Regulator | Intronic MAPT variant that regulates tau exon 3 splicing via hnRNP F/Q bindin... | Neurology & Cognition | Strong | |
| rs242557 | MAPT H1c Sub-haplotype Tag | Intronic MAPT variant tagging the H1c sub-haplotype within the H1 clade, inde... | Neurology & Cognition | Strong | |
| rs2471738 | MAPT H1c Sub-haplotype Tag (rs2471738) | Intronic MAPT variant whose T allele co-defines the H1c sub-haplotype, indepe... | Neurology & Cognition | Strong | |
| rs2583988 | SNCA | SNCA upstream regulatory variant (near gene-5) that is part of the 4-SNP SNCA... | Neurology & Cognition | Emerging | |
| rs2736990 | SNCA | Intronic SNCA variant (intron 4) associated with Parkinson's disease risk and... | Neurology & Cognition | Strong | |
| rs34311866 | TMEM175 | Lysosomal K+/H+ channel variant (p.Met393Thr) that impairs lysosomal pH regul... | Neurology & Cognition | Strong | |
| rs356182 | SNCA | Parkinson's disease GWAS risk variant affecting alpha-synuclein expression an... | Neurology & Cognition | Strong | |
| rs356219 | SNCA | SNCA 3′-region regulatory variant that upregulates alpha-synuclein expression... | Neurology & Cognition | Strong | |
| rs387907200 | SPR | Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe... | Methylation & Detox | Strong | |
| rs3756059 | SNCA | Intronic SNCA variant at the 5′ locus associated with REM sleep behavior diso... | Neurology & Cognition | Strong | |
| rs3785883 | MAPT H1h Sub-haplotype Tag | Intronic MAPT variant whose A allele defines the H1h sub-haplotype — a config... | Neurology & Cognition | Moderate | |
| rs76763715 | GBA N409S | GBA missense variant (p.Asn409Ser, formerly N370S) — the most common GBA path... | Neurology & Cognition | Established | |
| rs76904798 | LRRK2 5' Regulatory Variant | Common noncoding variant upstream of LRRK2 that increases gene expression in ... | Neurology & Cognition | Strong | |
| rs7697073 | SCARB2 | Intronic SCARB2 variant associated with REM sleep behavior disorder risk via ... | Neurology & Cognition | Moderate |