Research
Tag

Nutrition & Metabolism

17 genetic variants with this tag.

RSID Gene Description Category
rs1137101 LEPR Q223R (Gln223Arg) Common leptin receptor variant in the leptin-binding domain affecting satiety... Hormones & Sleep Moderate
rs2278651 SLC30A1 ZnT1 variant Intronic variant in SLC30A1 (ZnT1), the primary plasma-membrane zinc efflux t... Iron & Mineral Transport Emerging
rs174553 FADS1 Intronic variant in the FADS1 gene cluster that reduces delta-5 desaturase ac... Triglycerides & Fatty Acids Strong
rs475688 SLC22A12 Intronic regulatory variant in the URAT1 renal urate transporter gene; the T ... Uric Acid & Kidney Function Strong
rs16861205 ADIPOQ Intronic ADIPOQ variant in LD with the promoter region; the minor A allele is... Fat Storage & Energy Moderate
rs17606561 ELOVL2 3'-UTR variant in ELOVL2 associated with altered EPA-to-DHA conversion; A all... Triglycerides & Fatty Acids Moderate
rs17300539 ADIPOQ -11391G>A Promoter variant affecting adiponectin secretion and metabolic syndrome risk Fat Storage & Energy Strong
rs3832024 FMO3 FMO3 c.591_592del A 2-bp frameshift deletion in FMO3 that creates a premature stop codon at pos... Vitamins & Nutrient Absorption Established
rs1862513 RETN -420C>G Promoter variant that increases resistin expression via Sp1/Sp3 transcription... Fat Storage & Energy Moderate
rs2236212 ELOVL2 Intronic variant in ELOVL2 that reduces elongase-2 enzyme activity, impairing... Triglycerides & Fatty Acids Moderate
rs2727271 FADS2 Intronic variant in FADS2 (delta-6 desaturase) associated with reduced enzyme... Triglycerides & Fatty Acids Moderate
rs7359397 SH2B1 SH2B1 C/T Regulatory CpG-SNP downstream of SH2B1 that reduces gene expression via allel... Appetite & Obesity Moderate
rs266729 ADIPOQ -11391G>C Promoter variant reducing adiponectin transcription, increasing T2D, NAFLD, a... Fat Storage & Energy Strong
rs7498665 SH2B1 Thr484Ala Obesity GWAS missense variant in SH2B1 that impairs leptin signaling and incr... Appetite & Obesity Strong
rs3798713 ELOVL2 Intronic variant in ELOVL2 associated with altered plasma phospholipid PUFA l... Triglycerides & Fatty Acids Moderate
rs7061710 FMO3 Intronic FMO3 variant associated with reduced hepatic oxidation of garlic-der... Vitamins & Nutrient Absorption Moderate
rs953413 ELOVL2 Intronic enhancer variant in ELOVL2 that controls transcription factor bindin... Triglycerides & Fatty Acids Strong