Research
Tag

Neuroprotection

13 genetic variants with this tag.

RSID Gene Description Category
rs11136000 CLU Intronic variant in clusterin gene affecting Alzheimer's disease risk through... Neurology & Cognition Established
rs11931074 SNCA SNCA 3′-region variant in the extended 3′ UTR that affects alpha-synuclein mR... Neurology & Cognition Strong
rs1532278 CLU CLU Alzheimer's risk variant Intronic regulatory variant in CLU (clusterin/apolipoprotein J) that controls... Neurology & Cognition Strong
rs3758391 SIRT1 Promoter-region variant in SIRT1 affecting deacetylase expression; T allele e... Longevity & Aging Moderate
rs956572 BCL2 Intronic variant in the anti-apoptotic gene BCL2 that affects BCL2 expression... Mood & Behavior Moderate
rs2583988 SNCA SNCA upstream regulatory variant (near gene-5) that is part of the 4-SNP SNCA... Neurology & Cognition Emerging
rs2736990 SNCA Intronic SNCA variant (intron 4) associated with Parkinson's disease risk and... Neurology & Cognition Strong
rs7895833 SIRT1 A>G Intronic variant in SIRT1 affecting NAD-dependent deacetylase expression and ... Longevity & Aging Moderate
rs34311866 TMEM175 Lysosomal K+/H+ channel variant (p.Met393Thr) that impairs lysosomal pH regul... Neurology & Cognition Strong
rs356182 SNCA Parkinson's disease GWAS risk variant affecting alpha-synuclein expression an... Neurology & Cognition Strong
rs356219 SNCA SNCA 3′-region regulatory variant that upregulates alpha-synuclein expression... Neurology & Cognition Strong
rs7101429 GAB2 GAB2 Alzheimer's risk modifier Intronic variant in GAB2 that modulates late-onset Alzheimer's disease risk; ... Neurology & Cognition Moderate
rs76904798 LRRK2 5' Regulatory Variant Common noncoding variant upstream of LRRK2 that increases gene expression in ... Neurology & Cognition Strong