Tag
Methylation & Detox
14 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10483099 | QDPR | Intronic variant near QDPR that affects BH4 recycling efficiency, influencing... | Methylation & Detox | Emerging | |
| rs1049742 | AOC1 | Missense variant in the diamine oxidase enzyme that contributes to reduced hi... | Methylation & Detox | Moderate | |
| rs199971687 | MMAB | Pathogenic splice acceptor variant in MMAB that abolishes adenosylcobalamin s... | Vitamins & Nutrient Absorption | Established | |
| rs11683424 | DNMT3A | Intronic variant in the de novo DNA methyltransferase DNMT3A, associated with... | Methylation & Detox | Emerging | |
| rs13420827 | DNMT3A | 3' UTR variant in the de novo DNA methyltransferase DNMT3A, associated with a... | Methylation & Detox | Emerging | |
| rs162036 | MTRR K350R (Lys350Arg) | MTRR cobalamin-reactivation variant — reduces B12 recycling efficiency and mo... | Methylation & Detox | Moderate | |
| rs162040 | MTRR | Intronic MTRR tag SNP in a haplotype block where the C-allele variant associa... | Methylation & Detox | Emerging | |
| rs17309872 | GSS | Downstream regulatory variant of glutathione synthetase (GSS) associated with... | Methylation & Detox | Moderate | |
| rs202720 | FOLH1 | Intronic variant in the intestinal folate-cleaving enzyme FOLH1 (GCPII); the ... | Methylation & Detox | Emerging | |
| rs326124 | MTRR | Intronic MTRR variant associated with colorectal cancer survival in interacti... | Methylation & Detox | Emerging | |
| rs3776467 | MTRR | Intronic MTRR variant with sex-specific association with DNA methylation patt... | Methylation & Detox | Emerging | |
| rs3788189 | SLC19A1 SLC19A1 IVS2 variant | Intronic variant in the folate transporter gene associated with pemetrexed tr... | Methylation & Detox | Emerging | |
| rs387907200 | SPR | Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe... | Methylation & Detox | Strong | |
| rs71748309 | GSTT1 Null (Gene Deletion) | Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac... | Methylation & Detox | Strong |