Research
Tag

Immune Defense

9 genetic variants with this tag.

RSID Gene Description Category
rs146906133 FRMD5 FRMD5 UTI susceptibility variant Intronic variant in FRMD5 — a cell-adhesion scaffolding gene — where the rare... Innate Immunity & Infection Defense Emerging
rs1871534 SLC39A4 Leu372Val Common missense variant in the primary intestinal zinc transporter ZIP4; the ... Vitamins & Nutrient Absorption Strong
rs2976388 PSCA PSCA bladder urothelial variant Intronic PSCA variant that tags a regulatory region active in bladder urothel... Innate Immunity & Infection Defense Strong
rs3738198 SLC30A1 ZnT1 variant Intronic variant in the ZnT1 zinc efflux transporter gene; the minor C allele... Iron & Mineral Transport Emerging
rs35947132 PRF1 A91V Common perforin variant that reduces cytolytic activity by ~50%, acting as a ... Innate Immunity & Infection Defense Strong
rs763780 IL17F His161Arg Missense variant that reduces IL-17F bioactivity and acts as a natural IL-17F... TNF, NF-kB & Inflammatory Cytokines Moderate
rs7047299 IFNA21 Regulatory variant upstream of interferon alpha-21 associated with increased ... Innate Immunity & Infection Defense Moderate
rs73885319 APOL1 G1 S342G APOL1 G1 kidney disease risk variant — missense change that evolved for trypa... Cholesterol & Lipoproteins Established
rs35699176 ZNF77 ZNF77 Q100* Nonsense variant truncating ZNF77 at codon 100, impairing bronchial epithelia... Allergy & Atopic Disease Emerging