Tag
Immune & Antiviral
9 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs114947103 | CDHR3 CDHR3 intronic variant | Intronic CDHR3 variant in high linkage disequilibrium with the C529Y function... | Innate Immunity & Infection Defense | Moderate | |
| rs12252 | IFITM3 IFITM3 rs12252 (c.42T>C) | Splice-region synonymous variant in the innate antiviral gene IFITM3; the G a... | Innate Immunity & Infection Defense | Strong | |
| rs117648444 | IFNL4 Pro70Ser (P70S) | Missense variant in IFNL4 exon 2 that reduces IFN-λ4 protein activity; the Se... | Pharmacogenomics | Strong | |
| rs3077 | HLA-DPA1 HLA-DPA1 3′ UTR variant | Regulatory variant in the 3′ UTR of HLA-DPA1 that controls surface expression... | Interferon Signaling & Systemic Autoimmune | Strong | |
| rs3775291 | TLR3 Leu412Phe | Missense variant in TLR3 that halves dsRNA-binding capacity, reducing antivir... | Innate Immunity & Infection Defense | Strong | |
| rs7770370 | HLA-DPB1 | Intronic tag SNP in HLA-DPB1 (and upstream of HLA-DPA1) that marks the HLA-DP... | Interferon Signaling & Systemic Autoimmune | Strong | |
| rs9277535 | HLA-DPB1 | 3' UTR eQTL that reduces HLA-DPB1 expression, impairing antigen presentation ... | Interferon Signaling & Systemic Autoimmune | Strong | |
| rs368234815 | IFNL4 ss469415590 (TT/ΔG) | Causal frameshift polymorphism controlling IFNL4 protein production; the ΔG a... | Pharmacogenomics | Established | |
| rs6967330 | CDHR3 C529Y | Missense variant in the rhinovirus-C receptor CDHR3 that increases cell-surfa... | Allergy & Atopic Disease | Strong |