Research
Tag

HLA

23 genetic variants with this tag.

RSID Gene Description Category
rs12191877 HLA-C Tag for *06:02 Tag SNP for HLA-C*06:02, the strongest genetic risk factor for psoriasis, det... Psoriasis & Spondyloarthropathy
HLA
Established
rs1154155 TRA T-cell receptor alpha locus variant associated with narcolepsy susceptibility... Hormones & Sleep
HLA
Strong
rs17482078 ERAP1 R725Q Missense variant (Arg725Gln) in the ERAP1 peptide-binding domain that reduces... Psoriasis & Spondyloarthropathy
HLA
Strong
rs2187668 HLA-DQA1 DQ2.5 tag Tag SNP for HLA-DQ2.5 haplotype, the strongest genetic risk factor for celiac... Interferon Signaling & Systemic Autoimmune
HLA
Established
rs3077 HLA-DPA1 HLA-DPA1 3′ UTR variant Regulatory variant in the 3′ UTR of HLA-DPA1 that controls surface expression... Interferon Signaling & Systemic Autoimmune
HLA
Strong
rs419788 SKIV2L Intronic SKIV2L variant in the MHC class III region; the T allele tags an ind... Interferon Signaling & Systemic Autoimmune
HLA
Moderate
rs3129878 HLA-DRA HLA-DRA Variant Intronic variant in the HLA class II region associated with nonobstructive az... Endometriosis & Uterine Health
HLA
Strong
rs660895 HLA-DRB1 Regulatory tag SNP in the HLA-DRB1 region; the G allele marks the HLA-DRB1*04... Interferon Signaling & Systemic Autoimmune
HLA
Strong
rs6910071 TSBP1 MHC-region intronic variant tagging HLA-DRB1 shared epitope haplotypes; G all... Interferon Signaling & Systemic Autoimmune
HLA
Strong
rs4349859 HLA-B HLA-B27 proxy Intronic tag SNP located 41 kb centromeric of HLA-B and 5.4 kb telomeric of M... Psoriasis & Spondyloarthropathy
HLA
Established
rs4406273 HLA-C Near-HLA-C intergenic variant that tags HLA-C*06:02 haplotype, conferring ris... Psoriasis & Spondyloarthropathy
HLA
Strong
rs498422 LOC101929163 LOC101929163 Variant Intronic variant in TSBP1-AS1 (LOC101929163), a non-coding antisense RNA in t... Endometriosis & Uterine Health
HLA
Emerging
rs7770370 HLA-DPB1 Intronic tag SNP in HLA-DPB1 (and upstream of HLA-DPA1) that marks the HLA-DP... Interferon Signaling & Systemic Autoimmune
HLA
Strong
rs9268839 HLA-DRA Intergenic tag SNP upstream of HLA-DRA; the G allele is the primary GWAS sign... Interferon Signaling & Systemic Autoimmune
HLA
Strong
rs9277535 HLA-DPB1 3' UTR eQTL that reduces HLA-DPB1 expression, impairing antigen presentation ... Interferon Signaling & Systemic Autoimmune
HLA
Strong
rs17612852 HLA-DQA1 HLA-DQA1 Peanut Allergy Tag SNP Intronic tag SNP in HLA-DQA1 in strong LD with HLA-DQA1*01:02; the G allele i... Allergy & Atopic Disease
HLA
Strong
rs2040410 HLA-DQA1 HLA-DQ Autoimmune Tag SNP Intronic tag SNP near HLA-DQA1 that marks the DR3 (DRB1*0301-DQA1*0501-DQB1*0... Allergy & Atopic Disease
HLA
Strong
rs3129934 HLA-DRB5 DR15 haplotype tag Tag SNP for HLA-DRB5*01:01 on the DR15 susceptibility haplotype, physically n... Neurology & Cognition
HLA
Strong
rs3135388 HLA-DRA Tag for DRB1*15:01 Tag SNP for HLA-DRB1*15:01 (physically located near HLA-DRA), the strongest g... Neurology & Cognition
HLA
Established
rs7192 HLA-DRA HLA-DRA Leu242Val Missense variant (Leu242Val) in the HLA-DRA alpha chain; the T allele tags HL... Allergy & Atopic Disease
HLA
Strong
rs9275596 HLA-DQ HLA-DQ Region Peanut Allergy Locus Intergenic tag SNP between HLA-DQB1 and HLA-DQA2 tagging the HLA-DQA1*01:02 r... Allergy & Atopic Disease
HLA
Strong
rs9271366 HLA-DQA1 eQTL Intergenic eQTL near HLA-DQA1 that tags the DR15 haplotype (DRB1*15:01/DQA1*0... Neurology & Cognition
HLA
Established
rs9275328 HLA-DQB1 DQB1 region Intergenic SNP between HLA-DQB1 and HLA-DQA2 that tags the DQB1*06:02 allele,... Neurology & Cognition
HLA
Strong