Tag
Histamine
9 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10156191 | AOC1 Thr16Met | DAO structural variant affecting enzyme activity and histamine degradation | Methylation & Detox | Strong | |
| rs1049742 | AOC1 | Missense variant in the diamine oxidase enzyme that contributes to reduced hi... | Methylation & Detox | Moderate | |
| rs1049793 | AOC1 His645Asp | DAO structural variant near the catalytic domain affecting histamine degradation | Methylation & Detox | Strong | |
| rs1050891 | HNMT 3'UTR variant | Histamine breakdown in blood and tissues - uses methyl groups from SAM | Methylation & Detox | Moderate | |
| rs11558538 | HNMT Thr105Ile | HNMT structural variant - reduces enzyme stability and histamine clearance in... | Methylation & Detox | Strong | |
| rs1799983 | NOS3 Glu298Asp | Nitric oxide production - reduced activity increases cardiovascular risk and ... | Methylation & Detox | Established | |
| rs2052129 | AOC1 promoter variant | Histamine breakdown in gut - reduced activity means dietary histamine accumul... | Methylation & Detox | Strong | |
| rs2070744 | NOS3 T-786C promoter | NOS3 expression - controls how much eNOS enzyme is produced for nitric oxide ... | Methylation & Detox | Strong | |
| rs4684059 | HRH1 | Intronic variant in the histamine H1 receptor gene associated with altered re... | Methylation & Detox | Emerging |