Tag
Gut Barrier
9 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1050152 | SLC22A4 OCTN1 L503F | Missense variant in SLC22A4 encoding the organic cation/ergothioneine transpo... | Allergy & Atopic Disease | Strong | |
| rs10758669 | JAK2 | Intergenic variant near JAK2 that increases JAK2 expression and JAK-STAT sign... | IBD & Mucosal Immunity | Strong | |
| rs11229030 | PRG2 | Intergenic tag SNP in the PRG2/PRG3 eosinophil major basic protein gene clust... | Allergy & Atopic Disease | Moderate | |
| rs2108225 | SLC26A3 SLC26A3 Ulcerative Colitis Susceptibility Variant | Regulatory variant at the SLC26A3 locus associated with ulcerative colitis su... | Autoimmune Tolerance & T-Cell Regulation | Moderate | |
| rs2230926 | TNFAIP3 F127C | Missense variant in the A20 ubiquitin-editing enzyme that weakens NF-kB negat... | TNF, NF-kB & Inflammatory Cytokines | Strong | |
| rs1800972 | DEFB1 DEFB1 -44C>G | Promoter variant in the beta-defensin 1 gene that reduces constitutive hBD-1 ... | IBD & Mucosal Immunity | Moderate | |
| rs2066847 | NOD2 3020insC (1007fs) | The most important Crohn's disease risk variant worldwide — a frameshift inse... | IBD & Mucosal Immunity | Established | |
| rs2631367 | SLC22A5 OCTN2 -207C>G | Promoter variant in SLC22A5 (OCTN2) that reduces carnitine transporter expres... | IBD & Mucosal Immunity | Strong | |
| rs5029939 | TNFAIP3 | Intronic variant near TNFAIP3 that tags a 6q23 haplotype strongly associated ... | TNF, NF-kB & Inflammatory Cytokines | Strong |