Research
Tag

Growth Factors

11 genetic variants with this tag.

RSID Gene Description Category
rs1059369 GDF15 S48T GDF15 signal-peptide missense variant that tags a haplotype influencing circu... Fat Storage & Energy Moderate
rs12946942 SOX9 Intergenic variant in the SOX9 upstream regulatory region on chromosome 17q24... Innate Immunity & Infection Defense Strong
rs2178575 ERBB4 ERBB4/HER4 PCOS Folliculogenesis An intronic variant in ERBB4 on chromosome 2q34; the A allele tags reduced ER... Fertility & Ovarian Function Strong
rs1805097 IRS2 Gly1057Asp Missense IRS2 variant where Asp/Asp homozygotes are twice as likely to reach ... Longevity & Aging Moderate
rs1800471 TGFB1 R25P (Arg25Pro) Signal-peptide missense variant altering TGF-β1 secretion levels, associated ... Vascular Inflammation & Remodeling Moderate
rs35333564 MIR4300HG AIS Progression Locus (intron 1 enhancer indel) Intronic indel in the MIR4300 host gene that reduces enhancer activity and MI... Innate Immunity & Infection Defense Moderate
rs2229765 IGF1R c.3179G>A (E1013E) Synonymous IGF1R variant associated with lower circulating IGF-1 levels and e... Longevity & Aging Moderate
rs1805086 MSTN K153R Affects myostatin's ability to limit muscle growth, influencing muscle mass a... Fitness & Body Moderate
rs200330818 GDF2 Rare missense variant in BMP9/GDF2 that impairs processing of the mature BMP9... Vascular Inflammation & Remodeling Moderate
rs7030781 VEGFA VEGFA Regulatory Co-variant Chromosome 9 regulatory co-variant near a lncRNA locus that co-segregates wit... Vascular Inflammation & Remodeling Emerging
rs2854747 IGFBP3 Intronic variant in IGFBP3 — the gene encoding the main carrier protein for I... Fat Storage & Energy Moderate