Tag

Food Sensitivity

23 genetic variants with this tag.

RSID	Gene	Description	Category
rs10156191	AOC1 Thr16Met	DAO structural variant affecting enzyme activity and histamine degradation	Methylation & Detox	Food Sensitivity	Strong
rs1049742	AOC1	Missense variant in the diamine oxidase enzyme that contributes to reduced hi...	Methylation & Detox	Food Sensitivity	Moderate
rs1049793	AOC1 His645Asp	DAO structural variant near the catalytic domain affecting histamine degradation	Methylation & Detox	Food Sensitivity	Strong
rs11204971	FLG FLG locus regulatory variant	Regulatory tag SNP in the filaggrin (FLG) locus associated with reduced FLG e...	Allergy & Atopic Disease	Food Sensitivity	Moderate
rs150597413	FLG S3247X	Nonsense variant eliminating filaggrin protein — a minor European FLG null al...	Skin & Eyes	Food Sensitivity	Strong
rs12934922	BCO1 Arg267Ser	Reduces beta-carotene to retinol (vitamin A) conversion efficiency, contribut...	Vitamins & Nutrient Absorption	Food Sensitivity	Strong
rs145946881	MCM6 -14010G>C	African lactase persistence variant — MCM6 enhancer SNP that controls LCT exp...	Vitamins & Nutrient Absorption	Food Sensitivity	Strong
rs397507563	FLG 3702delG	Frameshift deletion in the third filaggrin repeat domain — the third most com...	Skin & Eyes	Food Sensitivity	Established
rs558269137	FLG 2282del4	Frameshift deletion eliminating filaggrin protein, the second most common Eur...	Skin & Eyes	Food Sensitivity	Established
rs61816761	FLG R501X	Nonsense variant eliminating filaggrin protein, the major genetic risk factor...	Skin & Eyes	Food Sensitivity	Established
rs1295686	IL13 IL-13 Atopy Promoter Variant	Intronic variant in IL13 that tags the atopic risk haplotype; the minor T all...	Allergy & Atopic Disease	Food Sensitivity	Strong
rs370793608	ALDOB ALDOB Y204X	Nonsense variant in the aldolase B gene creating a premature stop codon at po...	Metabolic Enzymes & Rare Disorders	Food Sensitivity	Established
rs41380347	MCM6 G-13915T	East African lactase persistence allele — MCM6 enhancer SNP that independentl...	Vitamins & Nutrient Absorption	Food Sensitivity	Strong
rs17612852	HLA-DQA1 HLA-DQA1 Peanut Allergy Tag SNP	Intronic tag SNP in HLA-DQA1 in strong LD with HLA-DQA1*01:02; the G allele i...	Allergy & Atopic Disease	Food Sensitivity	Strong
rs601338	FUT2 W143X (Trp143Ter)	Determines secretor status — whether ABO blood group antigens are secreted in...	Vitamins & Nutrient Absorption	Food Sensitivity	Established
rs6420424	BCO1	Upstream regulatory variant near BCO1 that reduces beta-carotene to vitamin A...	Vitamins & Nutrient Absorption	Food Sensitivity	Moderate
rs2052129	AOC1 promoter variant	Histamine breakdown in gut - reduced activity means dietary histamine accumul...	Methylation & Detox	Food Sensitivity	Strong
rs7834555	BCO1	Intergenic GWAS tag SNP near the BCO1 pathway, associated with circulating be...	Vitamins & Nutrient Absorption	Food Sensitivity	Emerging
rs4684059	HRH1	Intronic variant in the histamine H1 receptor gene associated with altered re...	Methylation & Detox	Food Sensitivity	Emerging
rs4988235	LCT -13910C>T	Lactase persistence - ability to digest lactose (milk sugar) in adulthood	Methylation & Detox	Food Sensitivity	Established
rs61816766	FLG Filaggrin second variant	Intronic FLG-locus variant strongly associated with atopic dermatitis — the C...	Allergy & Atopic Disease	Food Sensitivity	Strong
rs7192	HLA-DRA HLA-DRA Leu242Val	Missense variant (Leu242Val) in the HLA-DRA alpha chain; the T allele tags HL...	Allergy & Atopic Disease	Food Sensitivity	Strong
rs9275596	HLA-DQ HLA-DQ Region Peanut Allergy Locus	Intergenic tag SNP between HLA-DQB1 and HLA-DQA2 tagging the HLA-DQA1*01:02 r...	Allergy & Atopic Disease	Food Sensitivity	Strong