Tag
Fitness
32 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1042713 | ADRB2 Arg16Gly | Beta-2 adrenergic receptor variant affecting receptor downregulation, exercis... | Fitness & Body | Strong | |
| rs1049434 | SLC16A1 A1470T | Primary lactate transporter in skeletal muscle — affects lactate clearance du... | Fitness & Body | Moderate | |
| rs1052373 | MYBPC3 | Cardiac myosin-binding protein variant strongly associated with endurance ath... | Fitness & Body | Strong | |
| rs10852521 | FTO | FTO intron 1 variant associated with BMI and body fat accumulation, with stro... | Fitness & Body | Moderate | |
| rs11549465 | HIF1A Pro582Ser | Master regulator of cellular oxygen response influencing endurance capacity, ... | Fitness & Body | Strong | |
| rs11842874 | MCF2L | Intronic variant in MCF2L that acts as a synovial eQTL — A allele carriers ha... | Fitness & Body | Strong | |
| rs12640088 | PPARGC1A | Intronic variant in PPARGC1A that may modulate PGC-1alpha expression and mito... | Fitness & Body | Emerging | |
| rs12722 | COL5A1 C/T 3'UTR | Collagen fibril assembly variant linked to soft tissue injury risk and tendon... | Fitness & Body | Moderate | |
| rs2303729 | LTBP4 | Missense variant in LTBP4 encoding Val194Ile; the A allele (Ile) forms the IA... | Gamete Quality & DNA Repair | Strong | |
| rs1421405659 | MYBPC1 Leu259Pro | Ultra-rare dominant missense variant in slow skeletal myosin-binding protein ... | Fitness & Body | Strong | |
| rs1572312 | NFIA-AS2 | Long non-coding RNA regulating erythropoiesis, influencing hemoglobin levels ... | Fitness & Body | Strong | |
| rs17602729 | AMPD1 C34T (Q12X) | Enzyme critical for energy production during high-intensity exercise; deficie... | Fitness & Body | Strong | |
| rs1799752 | ACE I/D (Alu insertion/deletion) | The causal ACE insertion/deletion structural variant — presence or absence of... | Fitness & Body | Strong | |
| rs1800764 | ACE Promoter T>C | Upstream promoter-region ACE variant on a separate LD block from the I/D poly... | Fitness & Body | Moderate | |
| rs1800795 | IL6 -174G/C | Promoter variant controlling interleukin-6 expression — affects inflammation,... | Fitness & Body | Strong | |
| rs1801252 | ADRB1 Ser49Gly | Beta-1 adrenergic receptor variant at position 49 affecting receptor downregu... | Fitness & Body | Strong | |
| rs1801253 | ADRB1 Arg389Gly | Beta-1 adrenergic receptor variant where Arg389 produces higher basal activit... | Fitness & Body | Strong | |
| rs1805086 | MSTN K153R | Affects myostatin's ability to limit muscle growth, influencing muscle mass a... | Fitness & Body | Moderate | |
| rs1815739 | ACTN3 R577X | Determines presence of alpha-actinin-3 protein in fast-twitch muscle fibers, ... | Fitness & Body | Strong | |
| rs2010963 | VEGFA G-634C (+405G>C) | Promoter variant affecting VEGF-A expression and angiogenesis, influencing mu... | Fitness & Body | Strong | |
| rs2402970 | NRF1 | Intronic NRF1 variant associated with baseline differences in ventilatory thr... | Longevity & Aging | Moderate | |
| rs2104772 | TNC | Affects tenascin C protein levels and elasticity, influencing tendon injury r... | Fitness & Body | Strong | |
| rs2228001 | XPC Lys939Gln | Missense variant in the DNA damage recognition gene XPC that reduces global-g... | Fitness & Body | Strong | |
| rs28937900 | FKRP L276I | The most common pathogenic mutation in FKRP causing limb-girdle muscular dyst... | Fitness & Body | Established | |
| rs4235308 | PPARGC1A | Intronic variant in the PGC-1alpha gene linked to population-specific type 2 ... | Fitness & Body | Emerging | |
| rs4341 | ACE I/D tag SNP | Tag SNP for the ACE insertion/deletion polymorphism — the C allele tracks the... | Fitness & Body | Strong | |
| rs62623713 | SYPL2 E99G | Low-frequency missense variant in SYPL2 associated with morbid obesity suscep... | Fitness & Body | Emerging | |
| rs63749869 | RYR1 R4861H (Arg4861His) | RYR1 missense variant causing malignant hyperthermia susceptibility and centr... | Fitness & Body | Established | |
| rs699 | AGT M235T | Angiotensinogen level variant affecting blood pressure, sodium sensitivity, a... | Fitness & Body | Strong | |
| rs7181866 | GABPB1 | Intronic variant in the mitochondrial biogenesis regulator NRF2, associated w... | Fitness & Body | Moderate | |
| rs8192678 | PPARGC1A Gly482Ser | Master mitochondrial biogenesis regulator — Ser482 variant reduces PGC-1alpha... | Fitness & Body | Strong | |
| rs6949152 | NRF1 | Intronic variant in the master mitochondrial biogenesis transcription factor ... | Longevity & Aging | Moderate |