Tag
Fibrinolysis
13 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs11220465 | ST3GAL4 ST3GAL4 VWF/FVIII Modifier | Common intronic variant in the ST3GAL4 sialyltransferase gene associated with... | Coronary Artery Disease & Atherosclerosis | Moderate | |
| rs13412535 | SERPINE2 | Intronic regulatory variant in SERPINE2 that modulates expression of Protease... | Coagulation & Clotting Factors | Strong | |
| rs1799889 | SERPINE1 PAI-1 4G/5G Promoter | Promoter insertion/deletion polymorphism that controls PAI-1 (plasminogen act... | Coagulation & Clotting Factors | Strong | |
| rs2731672 | F12 | Regulatory tag variant in the Factor XII locus associated with plasma FXII ac... | Coagulation & Clotting Factors | Strong | |
| rs4220 | FGB Arg448Lys (R448K) | Missense variant in the fibrinogen beta chain that elevates circulating fibri... | Coagulation & Clotting Factors | Moderate | |
| rs5985 | F13A1 Val34Leu | Missense variant in Factor XIII A subunit; the Leu34 allele accelerates throm... | Coagulation & Clotting Factors | Strong | |
| rs6050 | FGA Thr312Ala | Missense variant in the fibrinogen alpha chain (FGA) that substitutes alanine... | Coagulation & Clotting Factors | Strong | |
| rs41276738 | VWF p.Arg854Gln (R854Q) type 2N | Missense variant in the VWF D' domain that abolishes high-affinity Factor VII... | Von Willebrand & Anticoagulant Proteins | Established | |
| rs35257264 | ST3GAL4 | Intronic variant near ST3GAL4 that modulates VWF and Factor VIII sialylation,... | Coronary Artery Disease & Atherosclerosis | Strong | |
| rs4252130 | PLG PLG promoter/intronic variant | Intronic PLG variant tagging a regional haplotype that reduces plasminogen ex... | Innate Immunity & Infection Defense | Moderate | |
| rs4252185 | PLG | Intronic PLG variant (intron 1) whose C allele is enriched in Europeans and a... | Innate Immunity & Infection Defense | Emerging | |
| rs6797312 | SERPINI1 | Intronic variant in the neuroserpin gene; the A allele has been associated wi... | Coronary Artery Disease & Atherosclerosis | Emerging | |
| rs73015965 | PLG Lys38Glu (K38E) | Missense variant in plasminogen that reduces fibrinolytic activity and impair... | Innate Immunity & Infection Defense | Strong |