Tag
Fat Distribution
19 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10195252 | GRB14/COBLL1 | Intergenic variant between GRB14 and COBLL1 that acts as an eQTL for GRB14 in... | Blood Sugar & Diabetes | Strong | |
| rs10852521 | FTO | FTO intron 1 variant associated with BMI and body fat accumulation, with stro... | Fitness & Body | Moderate | |
| rs150090666 | PDE3B PDE3B R783X | Loss-of-function variant in phosphodiesterase 3B — carriers have enhanced cAM... | Triglycerides & Fatty Acids | Strong | |
| rs11152221 | MC4R MC4R Proximal LD Block Variant | Intergenic variant in the proximal 3' regulatory block near MC4R associated w... | Appetite & Obesity | Strong | |
| rs12094543 | ZMYM4 ZMYM4 rs12094543 | Intronic variant in ZMYM4, a chromatin-remodeling transcription factor whose ... | Fat Storage & Energy | Emerging | |
| rs1943226 | MC4R MC4R third tagSNP | Upstream regulatory tag variant ~3 kb proximal to MC4R, included in MC4R hapl... | Appetite & Obesity | Emerging | |
| rs11705701 | IGF2BP2 IGF2BP2 Insulin Signaling Variant | Upstream regulatory variant in IGF2BP2 that shifts mRNA isoform balance in ad... | Blood Sugar & Diabetes | Moderate | |
| rs12490265 | PPARG PPARG Intronic Haplotype Variant | Intronic PPARG variant in a metabolic syndrome–associated haplotype block; th... | Fat Storage & Energy | Emerging | |
| rs2922126 | GHSR GHSR A/G (rs2922126) | Upstream regulatory variant near the ghrelin receptor gene; the A allele is a... | Appetite & Obesity | Moderate | |
| rs476828 | MC4R MC4R-region BMI variant | Intergenic variant in the MC4R regulatory haplotype block, tagging the same a... | Appetite & Obesity | Strong | |
| rs1797912 | PPARG PPARG intronic haplotype variant | Intronic PPARG variant in the same haplotype block as rs1175543; the C allele... | Fat Storage & Energy | Emerging | |
| rs2920502 | PPARG PPARG rs2920502 | Intronic PPARG variant associated with body fat percentage, impaired glucose ... | Fat Storage & Energy | Moderate | |
| rs62623713 | SYPL2 E99G | Low-frequency missense variant in SYPL2 associated with morbid obesity suscep... | Fitness & Body | Emerging | |
| rs3745012 | LPIN2 LPIN2 3'UTR variant | 3' UTR regulatory variant in LPIN2 (lipin 2) that alters fat distribution and... | Fat Storage & Energy | Moderate | |
| rs4684847 | PPARG PPARG cis-regulatory variant (PR domain recruitment) | Intronic cis-regulatory PPARG variant where the C allele recruits PR domain r... | Fat Storage & Energy | Moderate | |
| rs4684854 | PPARG | Intergenic regulatory variant downstream of PPARG associated with central obe... | Fat Storage & Energy | Emerging | |
| rs3787348 | PTPN1 PTPN1 intronic variant | Intronic PTPN1 tag SNP within the 100-kb insulin-resistance haplotype block; ... | Blood Sugar & Diabetes | Moderate | |
| rs6981587 | ANK1 ANK1 small-ankyrin T2D locus variant | Intronic ANK1 variant at the NKX6-3/ANK1 type 2 diabetes locus; the T allele ... | Fat Storage & Energy | Moderate | |
| rs587777380 | DYRK1B H90P / H90R | Multi-allelic pathogenic locus — both H90P (T>G) and H90R (T>C) disrupt the D... | Blood Sugar & Diabetes | Strong |