Tag
Cortisol
15 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs104894085 | STAR Q258X (c.772C>T) | Nonsense mutation in STAR that abolishes steroidogenic acute regulatory prote... | Reproductive Hormones | Established | |
| rs10482605 | NR3C1 | NR3C1 promoter variant reducing glucocorticoid receptor transcription; G alle... | Longevity & Aging | Moderate | |
| rs10515522 | NR3C1 | Intronic NR3C1 variant associated with longevity in Polish nonagenarians and ... | Longevity & Aging | Emerging | |
| rs1360780 | FKBP5 Intronic C>T | Co-chaperone of the glucocorticoid receptor that regulates cortisol feedback ... | Mood & Behavior | Strong | |
| rs1743963 | SGK1 | Intronic SGK1 variant associated with depression susceptibility in coronary h... | Blood Pressure & Hypertension | Emerging | |
| rs137852689 | STAR R217T (Arg217Thr) | Pathogenic STAR variant that abolishes steroidogenic acute regulatory protein... | Reproductive Hormones | Established | |
| rs12086634 | HSD11B1 Intron 3 variant | Modulates local cortisol activation from cortisone in liver and adipose tissu... | Hormones & Sleep | Moderate | |
| rs258750 | NR3C1 NR3C1 Intronic Variant (c.2181+244A>G) | Intronic NR3C1 variant tagging glucocorticoid receptor gene haplotype blocks ... | Reproductive Hormones | Moderate | |
| rs6162 | CYP17A1 His46= | Synonymous coding variant in CYP17A1 that tags a haplotype linked to altered ... | Reproductive Hormones | Moderate | |
| rs41423247 | NR3C1 BclI | Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s... | Mood & Behavior | Strong | |
| rs80358216 | HSD3B2 Trp171X | Pathogenic nonsense variant introducing a premature stop codon at position 17... | Reproductive Hormones | Established | |
| rs2918418 | NR3C1 | Intronic NR3C1 variant with CC genotype enriched in Polish centenarians; GG g... | Longevity & Aging | Emerging | |
| rs2963154 | NR3C1 | Intronic NR3C1 variant with TT genotype enriched in Polish centenarians; C al... | Longevity & Aging | Emerging | |
| rs7647305 | ETV5 | GWAS obesity locus near ETV5 — affects hypothalamic appetite regulation and f... | Appetite & Obesity | Moderate | |
| rs9556979 | STK24 HPA Axis Regulation | Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur... | Mood & Behavior | Moderate |