Tag
Chronic Pain
11 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10167914 | IL1A IL1A Endometriosis Susceptibility Variant | A regulatory tag SNP in the IL1A/IL1B locus on chromosome 2q13; the G allele ... | Endometriosis & Uterine Health | Strong | |
| rs10456100 | KCNK5 | Intronic variant near KCNK5 that reduces TASK2 potassium channel expression a... | Neurology & Cognition | Strong | |
| rs11842874 | MCF2L | Intronic variant in MCF2L that acts as a synovial eQTL — A allele carriers ha... | Fitness & Body | Strong | |
| rs1800629 | TNF -308 G>A | Promoter variant increasing TNF-alpha production approximately 2-fold, associ... | TNF, NF-kB & Inflammatory Cytokines | Strong | |
| rs142885915 | NPSR1 NPSR1 Endometriosis Risk Variant | An intronic insertion/deletion variant in the neuropeptide S receptor 1 gene ... | Endometriosis & Uterine Health | Moderate | |
| rs71575922 | SYNE1 SYNE1 Endometriosis Pain Subphenotype Variant | An intronic variant in SYNE1 (Nesprin-1) at the 6q25.1 locus, first identifie... | Endometriosis & Uterine Health | Strong | |
| rs2078371 | TSPAN2 | Regulatory variant in the TSPAN2/NGF locus on chromosome 1p13; the C allele i... | Neurology & Cognition | Strong | |
| rs208294 | P2RX7 His155Tyr | Gain-of-function missense variant in the P2X7 ATP-gated receptor that increas... | Neurology & Cognition | Moderate | |
| rs3791033 | KDM4A | Intronic variant in KDM4A histone demethylase associated with problematic opi... | Pharmacogenomics | Moderate | |
| rs640561 | LRRIQ3 | Intergenic variant near LRRIQ3 associated with problematic opioid prescriptio... | Pharmacogenomics | Emerging | |
| rs7958311 | P2RX7 Arg270His | P2RX7 variant with a unique dual mechanism — gain-of-function in channel open... | Neurology & Cognition | Moderate |