Research
Tag

Caffeine

9 genetic variants with this tag.

RSID Gene Description Category
rs2470890 CYP1A2 Asn516= (exon 7) Synonymous variant in CYP1A2 exon 7 in linkage disequilibrium with the *1F hi... Cancer Risk Strong
rs2066853 AHR Arg554Lys Aryl hydrocarbon receptor variant in the transactivation domain that alters A... Hormones & Sleep Moderate
rs2069526 CYP1A2 -739T>G Intronic CYP1A2 variant near the 5' end; G allele is associated with altered ... Pharmacogenomics Emerging
rs4410790 AHR Regulatory variant 54 kb upstream of the aryl hydrocarbon receptor gene; the ... Hormones & Sleep Strong
rs5751876 ADORA2A 1976T>C Adenosine A2A receptor variant that determines individual sensitivity to caff... Hormones & Sleep Strong
rs72547511 CYP1A2 CYP1A2*15 (Pro42Arg) Rare CYP1A2 missense variant at the critical Pro42 position; nearly abolishes... Pharmacogenomics Moderate
rs72547515 CYP1A2 *16 (Arg377Gln) Nearly-inactive CYP1A2 missense variant — carriers have severely impaired met... Pharmacogenomics Moderate
rs72547516 CYP1A2 Ile386Val Rare CYP1A2 missense variant (Ile386Val) associated with potentially reduced ... Pharmacogenomics Emerging
rs72547517 CYP1A2 *8 CYP1A2*8 — near-complete loss-of-function missense variant causing severely r... Pharmacogenomics Strong