Tag
Anxiety
24 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1006737 | CACNA1C | L-type calcium channel gene variant affecting mood regulation, emotional proc... | Mood & Behavior | Strong | |
| rs1049353 | CNR1 3'UTR (G1359A) | Synonymous exon 4 variant in the cannabinoid receptor 1 gene; near an exon sp... | Mood & Behavior | Moderate | |
| rs10786831 | SORCS3 SORCS3 Depression Variant | Intronic variant in the neurotrophin sorting receptor SORCS3, the top GWAS hi... | Mood & Behavior | Strong | |
| rs10947690 | MDGA1 Leu61Pro | Missense variant in the inhibitory synapse regulator MDGA1 that impairs neuro... | Hormones & Sleep | Strong | |
| rs11599236 | SORCS3 SORCS3 Neurotrophin Sorting | Intronic variant in the BDNF-receptor trafficking gene SORCS3, associated wit... | Mood & Behavior | Strong | |
| rs12624433 | SLC12A5 KCC2 Chloride Transport | Intronic variant in SLC12A5 reducing KCC2 potassium-chloride cotransporter fu... | Mood & Behavior | Moderate | |
| rs2271933 | HCRTR1 Ile408Val | Missense variant in the orexin/hypocretin receptor 1 that alters G-protein si... | Mood & Behavior | Moderate | |
| rs2371365 | PCLO PCLO Presynaptic Scaffold | Intronic variant in the presynaptic scaffold gene PCLO linked to altered mono... | Mood & Behavior | Moderate | |
| rs25531 | SLC6A4 A>G | Promoter SNP near 5-HTTLPR that modifies serotonin transporter expression and... | Mood & Behavior | Moderate | |
| rs279858 | GABRA2 K132K | GABA-A receptor alpha-2 subunit variant affecting alcohol response, anxiety, ... | Mood & Behavior | Strong | |
| rs324420 | FAAH Pro129Thr | Affects anandamide levels through altered FAAH enzyme stability, influencing ... | Mood & Behavior | Strong | |
| rs34579341 | NEGR1 NEGR1 Neuronal Growth Regulator | Intronic tag SNP in NEGR1 affecting neuronal cell adhesion, hippocampal neuro... | Mood & Behavior | Strong | |
| rs41423247 | NR3C1 BclI | Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s... | Mood & Behavior | Strong | |
| rs4395923 | CYP7B1 CYP7B1 Neurosteroid Hydroxylase | Intronic variant in the brain neurosteroid hydroxylase gene affecting DHEA an... | Mood & Behavior | Emerging | |
| rs4570625 | TPH2 G-703T | Promoter variant affecting brain serotonin synthesis enzyme; influences emoti... | Mood & Behavior | Moderate | |
| rs4702 | FURIN proBDNF Processing Variant | A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si... | Mood & Behavior | Moderate | |
| rs228697 | PER3 Pro864Ala | Core clock gene variant that shifts circadian period length and influences mo... | Hormones & Sleep | Moderate | |
| rs72704544 | GPM6A GPM6A Neuronal Membrane Glycoprotein | Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do... | Mood & Behavior | Moderate | |
| rs4855559 | MYH15 | Intronic variant in the myosin heavy chain 15 gene associated with impaired c... | Cardiomyopathy & Structural Heart | Emerging | |
| rs73034295 | IGSF9B IGSF9B Inhibitory Synapse Adhesion | Intronic variant in the gene encoding the inhibitory synaptic adhesion protei... | Mood & Behavior | Emerging | |
| rs324981 | NPSR1 Asn107Ile | Gain-of-function missense variant in the neuropeptide S receptor that increas... | Hormones & Sleep | Moderate | |
| rs9556979 | STK24 HPA Axis Regulation | Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur... | Mood & Behavior | Moderate | |
| rs4746 | GLO1 Glu111Ala | Missense variant in glyoxalase 1 reducing enzyme activity, allowing methylgly... | Hormones & Sleep | Moderate | |
| rs5751876 | ADORA2A 1976T>C | Adenosine A2A receptor variant that determines individual sensitivity to caff... | Hormones & Sleep | Strong |