Tag
Antioxidants
25 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1001179 | CAT -262C>T | Catalase promoter variant affecting hydrogen peroxide clearance and antioxida... | Methylation & Detox | Strong | |
| rs10063949 | SLC23A1 SLC23A1 variant | Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... | Vitamins & Nutrient Absorption | Moderate | |
| rs1042522 | TP53 Pro72Arg | p53 codon 72 polymorphism producing two functionally distinct proteins — Arg7... | Longevity & Aging | Strong | |
| rs10490924 | ARMS2 A69S | Second strongest genetic risk factor for age-related macular degeneration, af... | Skin & Eyes | Established | |
| rs11057830 | SCARB1 | Intronic variant in SCARB1 that affects SR-BI receptor function and the intes... | Cholesterol & Lipoproteins | Moderate | |
| rs11057841 | SCARB1 | Intronic variant in SCARB1 that tags a haplotype affecting SR-BI receptor-med... | Cholesterol & Lipoproteins | Moderate | |
| rs11950646 | SLC23A1 | Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... | Vitamins & Nutrient Absorption | Moderate | |
| rs1050450 | GPX1 Pro198Leu | Selenium-dependent antioxidant enzyme that neutralizes hydrogen peroxide; the... | Methylation & Detox | Strong | |
| rs12704795 | PON2 PON2 intron 1 variant | Intronic PON2 haplotype tag; the A allele is associated with reduced intracel... | Vascular Inflammation & Remodeling | Moderate | |
| rs1056836 | CYP1B1 Leu432Val | Phase I detoxification enzyme that hydroxylates estradiol to potentially geno... | Methylation & Detox | Moderate | |
| rs2251780 | GSR | Intronic variant in the glutathione reductase gene affecting antioxidant defe... | Vitamins & Nutrient Absorption | Emerging | |
| rs2361502 | MROH2A | Intronic variant adjacent to the UGT1A gene cluster; C allele tags elevated s... | Metabolic Enzymes & Rare Disorders | Moderate | |
| rs2237583 | PON1 PON1 intron variant | Intronic PON1 variant that modulates arylesterase activity of the HDL-bound a... | Vascular Inflammation & Remodeling | Moderate | |
| rs3877899 | SELENOP Ala234Thr | Missense variant in selenoprotein P that alters selenium transport capacity; ... | Vitamins & Nutrient Absorption | Moderate | |
| rs1695 | GSTP1 Ile105Val | Phase II detoxification enzyme that conjugates glutathione to carcinogens, dr... | Methylation & Detox | Strong | |
| rs1800566 | NQO1 Pro187Ser (C609T) | Phase II detoxification enzyme that reduces quinones and recycles CoQ10 to it... | Methylation & Detox | Strong | |
| rs4729189 | PON2 | Intronic PON2 variant associated with variation in serum paraoxonase activity... | Vascular Inflammation & Remodeling | Emerging | |
| rs705379 | PON1 PON1 promoter -108C>T | Promoter polymorphism that controls PON1 gene expression — the T allele (A on... | Vascular Inflammation & Remodeling | Strong | |
| rs6133175 | SLC23A2 | Intronic variant in the tissue vitamin C transporter SVCT2 — GG homozygotes c... | Vitamins & Nutrient Absorption | Moderate | |
| rs854555 | PON1 PON1 3'UTR variant | Intronic/downstream PON1 haplotype-tagging variant associated with PON1 activ... | Vascular Inflammation & Remodeling | Emerging | |
| rs854572 | PON1 PON1 promoter -909G>C | Promoter polymorphism that modulates PON1 gene expression level — the G allel... | Vascular Inflammation & Remodeling | Moderate | |
| rs6596471 | SLC23A1 SLC23A1 variant | Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... | Vitamins & Nutrient Absorption | Moderate | |
| rs6596473 | SLC23A1 SLC23A1 variant | Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... | Vitamins & Nutrient Absorption | Emerging | |
| rs6721961 | NFE2L2 | Promoter variant reducing NRF2 transcriptional activity by >50%, impairing th... | Longevity & Aging | Moderate | |
| rs4880 | SOD2 Val16Ala | Primary mitochondrial antioxidant enzyme - variant reduces superoxide detoxif... | Methylation & Detox | Strong |