Research
Tag

Angiogenesis

22 genetic variants with this tag.

RSID Gene Description Category
rs10958409 SOX17 Intergenic variant near SOX17 at 8q11 that reduces expression of this endothe... Vascular Inflammation & Remodeling Strong
rs11549465 HIF1A Pro582Ser Master regulator of cellular oxygen response influencing endurance capacity, ... Fitness & Body Strong
rs11967262 VEGFA Regulatory variant ~7 kb upstream of VEGFA linked to elevated varicose vein r... Vascular Inflammation & Remodeling Moderate
rs1333040 CDKN2B-AS1 9p21 locus variant in the ANRIL long non-coding RNA gene associated with intr... Coronary Artery Disease & Atherosclerosis Strong
rs1746048 CXCL12 Regulatory variant 80 kb downstream of CXCL12 on chromosome 10q11; the T alle... Coronary Artery Disease & Atherosclerosis Strong
rs1903068 KDR KDR/VEGFR2 Endometriosis Angiogenesis Variant Intergenic variant ~17 kb upstream of KDR (encoding VEGFR2, the primary VEGF ... Endometriosis & Uterine Health Strong
rs3738919 ITGAV ITGAV integrin alpha-V variant Intronic ITGAV variant associated with rheumatoid arthritis susceptibility in... B-Cell Immunity & Antibody-Mediated Disease Emerging
rs30021 SNX24 VEGFA Vascular Growth Co-variant Intronic variant in SNX24 (sorting nexin 24) with roles in vascular endotheli... Coronary Artery Disease & Atherosclerosis Emerging
rs200330818 GDF2 Rare missense variant in BMP9/GDF2 that impairs processing of the mature BMP9... Vascular Inflammation & Remodeling Moderate
rs2010963 VEGFA G-634C (+405G>C) Promoter variant affecting VEGF-A expression and angiogenesis, influencing mu... Fitness & Body Strong
rs6841581 EDNRA Regulatory variant upstream of the endothelin receptor type A gene that reduc... Blood Pressure & Hypertension Strong
rs2104772 TNC Affects tenascin C protein levels and elasticity, influencing tendon injury r... Fitness & Body Strong
rs28936687 ACVRL1 Pathogenic missense variant in ALK1 kinase domain causing hereditary hemorrha... Vascular Inflammation & Remodeling Established
rs2672598 HTRA1 Promoter variant at -487 in HTRA1 that elevates HTRA1 serine protease express... Longevity & Aging Strong
rs501120 CXCL12 Regulatory variant ~80 kb downstream of CXCL12 (SDF-1) associated with elevat... Coronary Artery Disease & Atherosclerosis Strong
rs17857135 RNF213 Met270Thr Missense variant (Met270Thr) in RNF213, the major moyamoya disease susceptibi... Neurology & Cognition Strong
rs7030781 VEGFA VEGFA Regulatory Co-variant Chromosome 9 regulatory co-variant near a lncRNA locus that co-segregates wit... Vascular Inflammation & Remodeling Emerging
rs41309766 NOTCH1 c.4512del (p.Cys1505fs) Pathogenic frameshift deletion in NOTCH1 causing haploinsufficiency; carriers... Cardiomyopathy & Structural Heart Strong
rs700651 BOLL Intronic variant near the BOLL gene associated with increased intracranial an... Coronary Artery Disease & Atherosclerosis Moderate
rs7025486 DAB2IP DAB2IP intron variant Intronic variant in DAB2IP associated with increased risk of abdominal aortic... Coronary Artery Disease & Atherosclerosis Strong
rs767603 LOC105378189 Regulatory variant near LOC105378189 non-coding RNA locus on chromosome 14q23... Coronary Artery Disease & Atherosclerosis Moderate
rs9298506 SOX17 Regulatory tag variant near SOX17 at chromosome 8q11.23 associated with intra... Vascular Inflammation & Remodeling Strong