Research
Tag

Adipogenesis

44 genetic variants with this tag.

RSID Gene Description Category
rs1044471 ADIPOR2 ADIPOR2 3'UTR variant A common 3'UTR variant in the liver-expressed adiponectin receptor 2 gene; th... Fat Storage & Energy Moderate
rs1058322 ADIPOR2 Intronic ADIPOR2 variant whose T allele reduces receptor expression in immune... Fat Storage & Energy Moderate
rs1063537 ADIPOQ 3'UTR variant in ADIPOQ that modulates adiponectin mRNA stability; the common... Fat Storage & Energy Moderate
rs10838738 MTCH2 Intronic GWAS obesity variant in MTCH2 — affects mitochondrial energy balance... Appetite & Obesity Moderate
rs10848554 ADIPOR2 Intronic ADIPOR2 variant co-associated with cardiovascular disease risk in in... Fat Storage & Energy Moderate
rs10865710 PPARG PPARG C-681G PPARG promoter-region enhancer variant that reduces PPARgamma expression, inc... Fat Storage & Energy Moderate
rs10882283 RBP4 RBP4 rs10882283 5' UTR variant in RBP4 that influences expression of retinol binding protein ... Fat Storage & Energy Moderate
rs11061937 ADIPOR2 ADIPOR2 rs11061937 Intronic ADIPOR2 variant associated with cardiovascular disease risk in indiv... Fat Storage & Energy Moderate
rs1151996 PPARG PPARG rs1151996 Intronic PPARG variant significantly associated with circulating vitamin D le... Fat Storage & Energy Moderate
rs1152003 PPARG PPARG 3'-flanking region variant — the G allele independently tags a PPARG re... Fat Storage & Energy Emerging
rs1175543 PPARG PPARG rs1175543 Intronic PPARG variant in strong linkage disequilibrium with rs709158; the G ... Fat Storage & Energy Emerging
rs1175544 PPARG PPARG rs1175544 Intronic PPARG variant that accounts for ~7% of individual variation in body ... Fat Storage & Energy Emerging
rs12094543 ZMYM4 ZMYM4 rs12094543 Intronic variant in ZMYM4, a chromatin-remodeling transcription factor whose ... Fat Storage & Energy Emerging
rs12490265 PPARG PPARG Intronic Haplotype Variant Intronic PPARG variant in a metabolic syndrome–associated haplotype block; th... Fat Storage & Energy Emerging
rs12636454 PPARG PPARG rs12636454 Intronic PPARG variant associated with modest reduction in type 2 diabetes ri... Fat Storage & Energy Emerging
rs16861194 ADIPOQ -11426A>G Upstream promoter variant that reduces ADIPOQ transcription, lowering circula... Fat Storage & Energy Moderate
rs16861205 ADIPOQ Intronic ADIPOQ variant in LD with the promoter region; the minor A allele is... Fat Storage & Energy Moderate
rs29941 KCTD15 GWAS obesity locus near KCTD15 — modulates adipogenesis through AP-2 transcri... Appetite & Obesity Moderate
rs16928751 ADIPOR2 ADIPOR2 CVD co-association variant Synonymous coding variant in ADIPOR2 (Q265Q) that was co-associated with card... Fat Storage & Energy Emerging
rs17036314 PPARG Intronic PPARG variant — carriers of the C allele have elevated fasting gluco... Fat Storage & Energy Moderate
rs1797912 PPARG PPARG intronic haplotype variant Intronic PPARG variant in the same haplotype block as rs1175543; the C allele... Fat Storage & Energy Emerging
rs1801282 PPARG Pro12Ala Insulin sensitivity - affects how well your cells respond to insulin Fat Storage & Energy Established
rs182052 ADIPOQ ADIPOQ promoter -10066A>G Intronic/promoter-region ADIPOQ variant where the A allele reduces circulatin... Fat Storage & Energy Strong
rs2241767 ADIPOQ +349A>G Intronic variant in the adiponectin gene associated with lower circulating ad... Fat Storage & Energy Moderate
rs2279525 PPARGC1A PPARGC1A 3' UTR metabolic association variant 3' UTR variant in the PGC-1alpha gene that may alter PPARGC1A mRNA stability ... Fat Storage & Energy Emerging
rs6947337 INHBA Activin A signaling variant near INHBA linking adipocyte dysfunction to share... Appetite & Obesity Moderate
rs2920502 PPARG PPARG rs2920502 Intronic PPARG variant associated with body fat percentage, impaired glucose ... Fat Storage & Energy Moderate
rs2959272 PPARG PPARG intronic calorie-restriction trial variant Intronic PPARG variant significantly associated with individual variation in ... Fat Storage & Energy Emerging
rs358806 WNT5A Regulatory variant near WNT5A linked to type 2 diabetes risk via impaired Wnt... Fat Storage & Energy Moderate
rs3211883 CD36 Intronic CD36 variant associated with altered body adiposity and platelet CD3... Triglycerides & Fatty Acids Moderate
rs3745012 LPIN2 LPIN2 3'UTR variant 3' UTR regulatory variant in LPIN2 (lipin 2) that alters fat distribution and... Fat Storage & Energy Moderate
rs3774261 ADIPOQ ADIPOQ rs3774261 Intronic ADIPOQ variant that reduces circulating adiponectin levels in G alle... Fat Storage & Energy Moderate
rs3856806 PPARG His477His (C1431T) Synonymous PPARG variant where the T allele reduces type 2 diabetes risk and ... Fat Storage & Energy Strong
rs4684847 PPARG PPARG cis-regulatory variant (PR domain recruitment) Intronic cis-regulatory PPARG variant where the C allele recruits PR domain r... Fat Storage & Energy Moderate
rs4684854 PPARG Intergenic regulatory variant downstream of PPARG associated with central obe... Fat Storage & Energy Emerging
rs367643250 DYRK1B R102C Rare gain-of-function variant causing autosomal dominant metabolic syndrome (... Blood Sugar & Diabetes Strong
rs4783244 CDH13 Intronic CDH13 variant altering T-cadherin expression; T allele carriers have... Triglycerides & Fatty Acids Strong
rs6809631 PPARG Intronic PPARG promoter tagSNP associated with modest reduction in type 2 dia... Fat Storage & Energy Emerging
rs6954668 SFRP5 SFRP5 Wnt5a inhibitor variant Intergenic variant near the SFRP5 adipokine locus; the A allele is strongly e... Fat Storage & Energy Emerging
rs709158 PPARG Intronic PPARG variant in strong linkage disequilibrium with rs1175543; the G... Fat Storage & Energy Emerging
rs7649970 PPARG PPARG C-689T PPARG PPARγ2 P2 promoter variant that reduces basal promoter activity, elevat... Fat Storage & Energy Moderate
rs822391 ADIPOQ IVS1+407C>T Intronic variant in the adiponectin gene associated with circulating adiponec... Fat Storage & Energy Moderate
rs9491696 RSPO3 Intronic enhancer variant in RSPO3 that increases gene expression in adipocyt... Fat Storage & Energy Strong
rs9817428 PPARG PPARG promoter tagSNP Intronic PPARG tagSNP with cross-ethnic replication for type 2 diabetes risk ... Fat Storage & Energy Emerging